T4 or MI?

Review: invasive management after unstable angina or non-ST-segment elevation MI does not reduce risk for death or MI.

M e t h o d s Data sources: MEDLINE and EMBASE/ Excerpta Medica (1966 to September 2003), and bibliographies of relevant articles. Study selection and assessment: Randomized controlled trials (RCTs), published in English, that compared invasive and noninvasive strategies for early management of patients with unstable angina or NSTEMI; had ≥ 3-month follow-up; and reported mortality, reinfarctio...

The "ARB-MI paradox": real or a fluke?

Aortic Dissection or MI? It could be both

Acute aortic dissection is a potentially lethal vascular emergency that involves the rapid development of a false blood channel within the media of the aorta. If left untreated, approximately 50% of patients die in the first 48 hours, and the mortality rate increases by 1% to 3% per hour [1,2]. Despite recent advances in diagnostic methods, misdiagnosis occurs in 25%-50% of patients on initial ...

Complicated colobomatous microphthalmia in the microphthalmic (mi/mi) mouse.

A study of the development of the eye in the cinnamon mouse, homozygous for the gene for microphthalmia (mi), has shown that the microphthalmia is due to failure of secondary vitreous formation associated with a coloboma. The retina is dystrophic but there is a residual population of large ganglion cells and the optic nerve also contains ganglion cells. All these ganglion cells have cytoplasm s...

t4 report1

1Department of Chemistry, Rutgers University, Camden, NJ, USA; Center for Computational and Integrative Biology, Rutgers University, Camden, NJ, USA 2Johns Hopkins Bloomberg School of Public Health, Center for Alternatives to Animal Testing (CAAT), Baltimore, MD, USA 3National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods, National Institute of En...